Goat Secondary Antibodies
Cayman Chemical 1,2,3-Tri-6(Z)-Octadecenoyl Glycerol, Purity: ≥98%, CAS: 3296-43-3, 10 mg
A triacylglycerol; has been found in plant seed oils
Cayman Chemical Flubendazole, Purity: ≥95%, CAS: 31430-15-6, 5 g
A benzimidazole carbamate anthelmintic; completely eliminates larvae in a mouse model of A. cantonensis infection and exhibits a mean larval reduction of 100% in a T. spiralis infection model at 5 and 50 mg/kg per day, respectively; inhibits mammalian tubulin polymerization (IC50 = 2.5 µM); inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin (IC50 = 0.17 µM); inhibits the proliferation of BT-549, SK-BR-3, MDA-MB-231, and MCF-7 breast cancer cells (IC50s = 0.72, 1.51, 1.75, and 5.51 µM, respectively); reduces tumor growth in an MDA-MB-231 mouse xenograft model at 25 mg/kg
Cayman Chemical Tioconazole, Purity: ≥95%, CAS: 65899-73-2, 1 g
An imidazole antifungal; inhibits the growth of various fungi, including C. albicans, C. neoformans, A. fumigatus, and T. rubrum (MICs = 4.7, 0.1, 5.7, and 0.5 µg/ml, respectively); inhibits C-14 demethylation of sterols in a cell-free C. albicans homogenate (IC50 = 50-80 nM); reduces the number of viable Candida cells recovered from the vagina in a mouse model of vaginal candidiasis at 2% w/v in a cream
Cayman Chemical Penfluridol, Purity: ≥98%, CAS: 26864-56-2, 1 g
A typical antipsychotic; binds to dopamine receptors (IC50 = 5.6 nM); binds to dopamine D4 and 5-HT receptors (Kis = 31 and 63.1 nM, respectively); inhibits stereotypic behavior induced by apomorphine in cynomolgus monkeys at 1.25 and 2.5 mg/kg; inhibits proliferation of TNBCs (IC50s = 6-8 µM); inhibits migration and invasion of TNBCs and decreases the expression of integrin α6 and β4; reduces tumor growth and metastasis in a 4T1 orthotopic mouse model at 10 mg/kg per day
Cayman Chemical Dexchlorpheniramine (maleate), Purity: ≥98%, CAS: 2438-32-6, 1 g
A histamine H1 receptor antagonist (pA2 = 9.36 in guinea pig ileal tissue); inhibits specific allergen-challenged peripheral blood mononuclear cell proliferation by 92% in vitro (4.8 µM); reduces noradrenaline uptake in rat vas deferens ex vivo (10 µM); increases pain threshold in mice exposed to thermal and chemical stimulation (30 mg/kg, i.p.)
Cayman Chemical Secoisolariciresinol Diglucoside, Purity: ≥98%, CAS: 158932-33-3, 100 mg
A lignan with diverse biological activities; scavenges DPPH radicals (IC50 = 78.9 μg/ml) in a cell-free assay; dose-dependently inhibits the growth of SW480 human colon cancer cells; dietary administration reduces the number of proliferating tumor cells in an MCF-7 human breast cancer mouse xenograft model in the presence of circulating estrogen; increases insulin and decreases glucose serum levels in rats with streptozotocin-induced diabetes at 20 mg/kg; decreases infarct size in rats with myocardial infarction induced by permanent occlusion of the left anterior descending coronary artery at a 20 mg/kg per day
Cayman Chemical LipidLaunch™ SORT LNP Exploration Kit, 1 ea
Cayman’s LipidLaunch™ SORT LNP Exploration Kit is intended to serve as a starting point for laboratories to explore the feasibility of using SORT LNPs for their individual application without the need for specialized equipment. Optimal preparation conditions for the encapsulation of nucleic acids with LNPs must be determined by the end user.
American Research Products Inc Anti ADAMTS10 Antibody
Anti-ADAMTS10 Rabbit Polyclonal Antibody Propeptide domain
American Research Products Inc Anti PCKS9 Antibody
Anti-PCKS9 Rabbit Polyclonal Antibody Catalytic domain
American Research Products Inc Anti CSTA Antibody
Anti-CSTA Rabbit Polyclonal Antibody Cartboxyterminus
Cayman Chemical Buffer Supplement (10X), 15 mL
Buffer Supplement (10X) has been tested and formulated to work exclusively with Cayman’s Senescence-Associated β-Galactosidase Staining Kit (Item No. 602010).
Cayman Chemical Dipeptide diaminobutyroyl benzylamide (hydrochloride), Purity: ≥98%, 250 mg
A biomimetic peptide and muscarinic acetylcholine receptor antagonist; blocks sodium uptake and induces muscle relaxation
Cayman Chemical Benzydamine (hydrochloride), Purity: ≥95%, CAS: 132-69-4, 25 g
An NSAID; decreases the viability of THP-1, Saos-2, and HGF-1 cells (IC50s = 59.08, 30.79, and 52.06 µg/ml, respectively); reduces LPS-induced increases in the levels of IL-6 and TNF-α secreted by THP-1 cells at 10 µg/ml; decreases PGE2 and PGF1α levels in unstimulated or IL-1β- or TNF-α-stimulated primary human gingival fibroblasts at 1 µM; reduces hydrochloric acid levels and increases mucin levels in gastric juices isolated from rats at 100 mg/kg; inhibits carrageenan-induced paw edema in rats at an oral dose of 60 mg/kg or applied topically at 3% (w/w)
American Research Products Inc Anti HTRA2 Antibody
Anti-HTRA2 Rabbit Polyclonal Antibody Catalytic domain
Cayman Chemical Sulfadimethoxine, Purity: ≥98%, CAS: 122-11-2, 5 g
A sulfonamide antibiotic; inhibits recombinant P. carinii DHPS (IC50 = 25 nM) in a cell-free assay; active against S. aureus, S. pneumoniae, K. pneumoniae, and E. coli in a disc assay; active against C. spiroforme isolates from rabbits (MIC90 = 256 μg/ml) and certain M. bovoculi isolates from keratoconjunctivitis infections in cows (MIC50 = ≤256 μg/ml); efficacious S. pneumoniae, K. pneumoniae, and E. coli systemic infections in mice (CD50s = 79.7, 2.7, and 12.2 mg/kg, respectively); efficacious against H. capsulatum systemic fungal infections in mice (CD50 = 300 mg/kg)